• anti-allergy
  • influenza prevention
  • immunostimulation

Lactobacillus acidophilus L-92

Lactobacillus acidophilus L-92

A lactic acid bacterial strain selected from the Asahi Group’s extensive library of proprietary lactic acid bacteria for its anticipated benefits in suppressing allergies.

Research background

The Asahi Group’s research on lactic acid bacteria and fermented milk can be traced back to Calpis, a company that produced and released Japan’s first lactic acid bacteria beverage in 1919. Tests done on mice in the 1970s as part of a collaborative research project between Calpis (then still an independent company) and Riken found that longevity was promoted by a proprietary formulation of fermented milk made from lactic acid bacteria and yeast. This work inspired the Asahi Group to pioneer the study of microorganisms and fermented milk by researching functional lactic acid bacteria.

Major research findings

  • Alleviation of hay fever symptoms
  • Alleviation of atopic dermatitis symptoms
  • Alleviation of perennial allergic rhinitis symptoms
  • Flu virus spread prevention
  • Inhibition of drops in immunity caused by summer heat

Creating a society of health and abundance

Lactobacillus acidophilus L-92 is known to act on the body’s immune function to provide a wide range of benefits that include allergy symptom relief and preventing the spread of infectious diseases. The immune system is a crucial bodily function that preserves health at every stage of life. Asahi should be able to help promote and maintain lifelong human health by providing a more complete scientific description of the relationship between Lactobacillus acidophilus L-92 and the immune system.

Research information on Lactobacillus acidophilus L-92

  • Paper

    Functional role of surface layer proteins of Lactobacillus acidophilus L-92 in stress tolerance and binding to host cell proteins

  • Paper

    Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis.

  • Paper

    Lactobacillus acidophilus CP23 with weak immunomodulatory activity lacks anchoring stucture for surface layer protein

  • Paper

    Lactobacillus acidophilus L-92 cells activate expression of immunomodulatory genes in THP-1

  • Paper

    Anti-influenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity

  • Paper

    Exposure to Probiotic Lactobacillus acidophilus L-92 Modulates Gene Expression Profiles of Epithelial Caco-2 Cells

  • Paper

    Transcriptional response of Lactobacillus acidophilus L-92 after attachment to epithelial Caco-2 cells

  • Paper

    Characterization of adhesive molecule with affinity to Caco-2 cells in Lactobacillus acidophilus by proteome analysis

  • Paper

    Effects of Oral Administration of Lactobacillus acidophilus L-92 on the Symptoms and Serum Markers of Atopic Dermatitis in Children.

  • Paper

    Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function.

  • Paper

    Lactobacillus acidophilus strain L-92 regulates the production of Th1 cytokines as well as Th2 cytokines.

  • Paper

    Effect of Milk Fermented with Lactobacillus acidophilus Strain L-92 on Symptoms of Japanese Cedar Pollen Allergy: A Randomized Placebo-Controlled Trial

  • Paper

    Clinical Effects of Lactobacillus acidophilus Strain L-92 on Perennial Allergic Rhinitis: A Double-Blind, Placebo-Controlled Study

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